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Prescription use of this product is limited under the Drug Addiction Treatment Act. Monitor patients for conditions indicative of diversion or progression of opioid dependence and addictive behaviors.

Risk of Respiratory Depression and Concomitant Use of Benzodiazepines or Other CNS Depressants with Buprenorphine: Buprenorphine has been associated with life-threatening respiratory depression, overdose, and death, particularly when misused by self-injection or with concomitant use of benzodiazepines or other CNS depressants, including alcohol. Use with caution in patients with compromised respiratory function e. Unintentional Pediatric Exposure: Buprenorphine can cause severe, possibly fatal, respiratory depression in children who are accidentally exposed to it. Neonatal Opioid Withdrawal Syndrome: Neonatal opioid withdrawal syndrome NOWS is an expected and treatable outcome of prolonged use of opioids during pregnancy.

NOWS may be life-threatening if not recognized and treated in the neonate. Newborns should be observed for signs of NOWS and managed accordingly.

Adrenal Insufficiency: Adrenal insufficiency has been reported with opioid use. If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. Hypersensitivity Reactions: Hypersensitivity to buprenorphine- and naloxone-containing products have been reported most commonly as rashes, hives, and pruritus.

Elevation of Cerebrospinal Fluid Pressure: Buprenorphine may elevate cerebrospinal fluid pressure and should be used with caution in patients with head injury, intracranial lesions, and other circumstances when cerebrospinal pressure may be increased.

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This is not a complete list of potential adverse events. Serotonergic Drugs: If concomitant use with serotonergic drugs is warranted, monitor for serotonin syndrome, particularly during treatment initiation and dose adjustment.

Pregnancy: Opioid-dependent women on buprenorphine maintenance therapy may require additional analgesia during labor. Advise breastfeeding women to monitor the infant for increased drowsiness and breathing difficulties.

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Fertility: Chronic use of opioids may cause reduced fertility. It is not known whether these effects on fertility are reversible. Contents may not be reproduced in any form except for personal use and may not be used on any other website without permission. NeedyMeds, a registered c 3 national nonprofit , makes every effort to ensure the accuracy of the information on the website. However, we can't guarantee the accuracy or completeness of the information.

Always check with the individual program if you have questions. Find help with the cost of medicine. Donate now. Help with Prescription Assistance Applications.

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Scroll down to find all drugs and dosages that can offer savings or information by clicking on the drug name then click on the icon: Patient Assistance Programs PAPs Programs created by pharmaceutical companies to provide free or discounted medicines to people who are unable to afford them. Each program has its own qualifying criteria.

Learn more Pharmacy retailers' prescription programs which offer generic medications for a discounted price. Offers of brand name medicine over-the-counter and prescription and medical supplies. In the form of a printable coupon, rebate, savings card, free trial offers or free samples.

Support Pages Support Pages offer a link to the product website where additional resources and services can be found. Typically offered by pharmaceutical companies, co-pay cards are designed to help people with private insurance for the co-payments required to obtain their prescriptions at the pharmacy. Videos on selected drugs with information on prescribing as well as patient package inserts, medication guides and consumer medication information.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Expiration Date: None. Addyi Free Trial: Eligible patients may receive the first 8 weeks of medication FREE regardless of insurance coverage; for additional information contact the program at Advate Freedom of Choice Free-Trial Program: Eligible patients may receive 6 free trial doses; for additional information contact the program at Advil Allergy and Congestion Relief.

Adynovate Freedom of Choice Free-Trial Program: Eligible patients may receive 8 free doses of medication; for additional information contact the program at Aldurazyme Charitable Access Program CAP : Program provides medication to patients who medically need it and are uninsured or underinsured; for additional information contact the program at , option 3.